Development of a new “Fast GC-MS” System for Multi-drug Analyses

This report details the incorporation of a recently installed “fast GC-MS” system to upgrade the existing GC-MS facility and complement the LC-MS provision for forensic analysis at Hampshire Scientific Service. Hampshire Scientific Services provides an analytical service for Coroners by screening toxicology exhibits for drugs and medicines and quantifying by LC-MS-MS where necessary. The software and hardware components were developed using a library built with standards. Optimisation steps included extension of the Agilent Deconvolution Reporting Software (DRS) which combines Chemstation, National Institute of Standards and Technology (NIST) and Automated Mass Spectral and Identification Software (AMDIS) to generate a bespoke compound mass spectral library. Secondly, a Nitrogen Phosphorous Detector (NPD) produces peak height data for standards and reference